L-Serine, an AminoAcid closely associated with sleep quality
L-Serine (L-Serine), mainly found in seaweeds, soy products, meat, nuts, legumes and dairy products, is one of the aliphatic polarAmino Acids, which belongs to the group of raw sugarAmino Acids. As a kind of basic amino acid of constituent proteins, L-Serine is an important precursor in the body involved in the synthesis of intracellular biological substances purine, pyrimidine, phospholipids, etc., so it is widely used in compound amino acid infusions, health products, special medical foods, L-Serine also has a special moisture and moisture retention, at home and abroad is widely used in advanced cosmetics, L-Serine as a beneficial nutrient element to humans, Having a role in aiding in conditioning neurotransmitter transmission, a recent study published by springerplus showed that L-Serine can significantly improve sleep initiation time and the number of nighttime awakenings in work stressed individuals, thus achieving a stress relief, balance emotions, and ultimately effective in improving sleep quality.
Industrially, L-Serine production methods mainly include proteolysis, chemical synthesis, and enzymatic conversion. Fermentation method is the main method of precursor glycine fermentation, by adding the precursor material to obtain serine, at present, the production has been reported. Proteolysis was performed using native protein as the starting material and resulted in a mixture of severalAmino Acids, after which L-Serine was obtained by crystallization in a purified manner. Chemical synthesis is very rarely used in the production of crude drugs and mainly suffers from some disadvantages such as high production cost, severe process pollution emission, and difficult separation between D-serine and L-Serine. The enzymatic method uses the reaction of glycine and aldehydes and has the advantages of high selectivity and product yield, but the harmful substance formaldehyde residue cannot be easily removed.
L-Serine produced in the pharmaceutical industry of spermatine avoids the deficiencies of the above methods, has the characteristics of few impurities, high purity, and no residual formaldehyde, which is very important for the downstream preparation of health care materials such as phosphatidylserine and cycloserine and pharmaceutical materials.
